1, The molecular basis of chemoresistance is poorly understood, precluding advances in glioma treatment and leaving gliomas among the most lethal tumors.

2, Objective:Chemoresistance is a major obstacle for successful gastric cancer treatment.

3, Conclusions Moderate dose of verapamil can reverse chemoresistance of pancreatic carcinoma cell line to ADM and MMC that might be related to MDR1.

4, The mechanism inducing chemoresistance of the different cells was not the same.

5, ConclusionThere exists internal relations between the chemoresistance and radiosensitivity of lung adenocarcinoma cisplatin-resistant cell, chemo-resistance leads to reduced radiosensitivity.

6, These findings show that methadone kills leukemia cells and breaks chemoresistance and apoptosis resistance.

7, It is concluded that by co-culture of cell-cell contact with MSC, growth suppression and induction of chemoresistance of K562 cells take place. The mechanism, however, seems not relevant with MDR1.

8, This study was designed to explore the role of apoptosis- associated genes and proteins on the chemoresistance in COC1/DDP.