1. This is that industrial output increased four-fold over the eighteenth century, home consumption of it three-fold and exports six-fold.

2. In some patients, there was four-fold increase in antibody response before the first sputum culture of P cepacia.

3. That is a nearly four-fold increase over the number who lost out under the old, more lenient rules.

4. Agricultural and fishing exports increased four-fold in value from 1974-77.

5. For example, the square has four-fold symmetry, the pentagon has five-fold,(sentencedict.com) the hexagon has six-fold symmetry.

6. TLS.AX) and Internet security specialists MessageLabs show a four-fold spike in the number of times employers have blocked access to social networking sites between June 2008 and April 2009.

7. Finally, crystallized D-ribose was precipitated by adding four-fold amount of ethanol into the enriched effluent.

8. The purposes are four-fold, with peace and development being the twin center pieces.

9. There has been a four-fold increase in couples breaking up for these reasons in the last two years, amid increasing financial strain on families.

10. As such, requirements must be considered from this four-fold vantage point, or in some similar manner.

11. The scheme offers the company the chance of a four-fold rise in audiences for a two-fold increase in money.

12. And scarily, rates of this skin-cancer type have increased four-fold in women under 40.

13. According to the plan, by 2020, China will produce ten million tonnes of fuel ethanol and two million tonnes of biodiesel(sentencedict.com), a four-fold increase on 2002 levels.

14. He hopes to improve the accuracy of his measurements four-fold within five years.

15. The Uganda National Tuberculosis and Leprosy Programme calculates that HIV has led to a four-fold increase in TB cases in that country alone.

16. Feeding all those chickens has also spurred a roughly four-fold growth in the domestic feed grain industry, she says.

17. An ongoing trial in Uganda shows that coverage rates have increased by from two-fold to four-fold.

18. There have been positive developments, such as H5N1 vaccines with adjuvants that reduce the dose of the vaccine required by four-fold.

19. In the last year alone referrals for talking therapies rose four-fold to nearly 600, 000, Department of Health figures showed.

20. Paracetamol doubled the risk, while ibuprofen or aspirin increased it four-fold.

21. Mobile phone clients are seen surging to 38 million in five years from 20.5 million now, while broadband clients may jump four-fold to 12 million from 3.15 million now.

22. Before 1970 only nine countries had experienced DHF epidemics, a number that had increased more than four-fold by 1995.

23. The image shows a eukaryotic voltage-dependent potassium channel viewed along the four-fold axis from the extracellular surface.

24. These children are not about to drop dead when they're 11 or 12 but it indicates they're a three or four-fold higher risk of heart attack in their 40s or 50s.

25. Overseas acquisitions by Japanese financials already total $12.5 billion this year, up four-fold from the same period last year, according to Thomson Reuters data.

26. For DB2 9.7, the limits on the size of large and temporary table spaces have been increased four-fold.