1. Vain glory blossoms but never bears. 
2. An old dog barks not in vain.
3. ’Tis altogether vain to learn wisdom and yet live foolishly.
4. She's very vain about her good looks.
5. Men can be just as vain as women.
6. We searched in vain for the missing child.
7. He was self-important, vain and ignorant.
7. Sentencedict.com is a online sentence dictionary, on which you can find good sentences for a large number of words.
8. Parents campaigned in vain for her reinstatement.
9. I think he is shallow, vain and untrustworthy.
10. I tried in vain to start a conversation.
11. She's just a vain, foolish woman.
12. They sought in vain for somewhere to shelter.
13. She is perceived as vain, spoilt and promiscuous.
14. He tried in vain to bring his temper under control.
15. We tried in vain to make him change his mind.
16. A seemingly endless line of trucks waits in vain to load up.
17. She closed her eyes tightly in a vain attempt to hold back the tears.
18. She is one of those vain people who never take others' advice.
19. I knocked loudly in the vain hope that someone might answer.
20. They endeavoured to make her happy but in vain.
21. Their lives have not been laid down in vain.
22. Doctors battled in vain to save his life.
23. They waited in vain for a response.
24. All our efforts were in vain.
25. All our work was in vain.
26. Police searched in vain for the missing gunman.
27. Money spent on the brain is never spent in vain.
28. The doctors gave him more powerful drugs in the vain hope that he might recover.
29. The drafting committee worked through the night in a vain attempt to finish on schedule.
30. All efforts to reconcile her with her husband were in vain.
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